FIG. 1.

Physical map of the HPI of Y. enterocolitica O8 WA-C with the presumed 5′ and 3′ borders of the HPI. Horizontal lines below the restriction map represent different subcloned DNA fragments (E6, E8.8, E3.5, and Cl8) which were used as probes in hybridization assays. Arrows and bars within the restriction map indicate the locations of the identified genes and repeated sequence (RS) elements, respectively. E, EcoRI; C, ClaI; p12H2 and p17A11, cosmid clones. The locations of the 5′-HPI probe and the adjacent asnT tRNA are indicated. The asterisk indicates an additional internal EcoRI site found only in the irp2 genes of Y. enterocolitica biotype 1B strains.