The IC₅₀ (μM) values of Dp4e4mT and its Fe(iii), Co(iii), Ni(ii), Cu(ii), Zn(ii), Ga(iii), and Pd(ii) complexes relative to the control agents, Dp44mT, DpC and DFO at inhibiting the growth of SK-N-MC and AsPC-1 cells, and mortal cell-type MRC-5 fibroblasts, as determined by the MTT assay after a 24, 48 and 72 h incubation at 37 °C. Results are mean ± SD (3 experiments).

Compounds	IC50 (μM)
	SK-N-MC			AsPC-1			MRC-5
	24 h	48 h	72 h	24 h	48 h	72 h	72 h
DFO	>100	45.270 ± 0.061	8.184 ± 2.460	>100	22.760 ± 0.084	3.074 ± 0.585	28.910 ± 0.101
Dp44mT	>25	0.043 ± 0.006	0.006 ± 0.001	4.636 ± 0.071	0.042 ± 0.006	0.015 ± 0.003	1.073 ± 0.007
DpC	22.300 ± 0.083	0.088 ± 0.007	0.028 ± 0.009	4.921 ± 0.034	0.087 ± 0.034	0.018 ± 0.007	2.987 ± 0.008
Dp4e4mT	>25	0.043 ± 0.006	0.006 ± 0.001	3.783 ± 0.091	0.045 ± 0.008	0.009 ± 0.002	1.811 ± 0.518
[Fe(Dp4e4mT)2]+	2.678 ± 0.071	1.531 ± 0.037	0.214 ± 0.005	22.380 ± 0.058	1.581 ± 0.077	0.201 ± 0.031	1.980 ± 0.006
[Co(Dp4e4mT)2]+	5.498 ± 0.004	1.474 ± 0.061	0.818 ± 0.051	9.522 ± 0.091	2.681 ± 0.078	1.570 ± 0.257	3.901 ± 0.007
[Ni(Dp4e4mT)2]	>25	0.075 ± 0.025	0.018 ± 0.006	>25	0.234 ± 0.083	0.076 ± 0.054	>5
[Cu(Dp4e4mT)Cl]	0.492 ± 0.034	0.031 ± 0.008	0.003 ± 0.001	1.074 ± 0.006	0.042 ± 0.006	0.003 ± 0.001	0.391 ± 0.072
[Cu(Dp4e4mT)2]	0.516 ± 0.006	0.034 ± 0.006	0.004 ± 0.001	1.142 ± 0.034	0.044 ± 0.007	0.003 ± 0.003	0.342 ± 0.121
[Zn(Dp4e4mT)2]	19.350 ± 0.081	0.044 ± 0.007	0.004 ± 0.002	1.728 ± 0.027	0.048 ± 0.007	0.006 ± 0.001	0.756 ± 0.093
[Ga(Dp4e4mT)2]+	16.220 ± 0.007	0.043 ± 0.006	0.004 ± 0.001	2.431 ± 0.015	0.047 ± 0.006	0.005 ± 0.001	0.774 ± 0.014
[Pd(Dp4e4mT)Cl]	>25	0.661 ± 0.062	0.285 ± 0.121	>25	1.341 ± 0.074	0.262 ± 0.078	1.040 ± 0.011