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Genes associated with RA and those identified with key driver gene (KDG) analyses. (A) Number of genes utilized for KDA analysis in two different lists. The intersection is calculated as |A ∩ B|/min(|A|, |B|). (B) Mean number of genes designated as KDG following KDA in various networks from the two lists.
| A. RA associated genes | B. Obtained KDGs (averg. over networks) | ||||
|---|---|---|---|---|---|
| Lit. list | DEG list | Overlap | Lit. KDG | DEG KDG | Overlap |
| 259 | 93 | 10% | 741 | 827 | 90% |
