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[Preprint]. 2023 Dec 28:2023.12.28.573261. [Version 1] doi: 10.1101/2023.12.28.573261

Table 11.

Compound results based on QSAR prediction.

Compound TLK2 Inhibition Activity (nM)
Predicted Found Log Predicted log Actual
117 51 23 7.29 7.64
118 56 36 7.25 7.44
119 50 77 7.30 7.11
120 370 27 6.44 7.57
121 68 180 7.17 6.74
122 180 47 6.75 7.33
123 1800 630 5.76 6.20
124 40 260 7.40 6.59
125 8 120 8.08 6.92
126 8 15 8.12 7.82
127 37 46 7.44 7.34
128 180 18 6.74 7.74
129 960 2600 6.02 5.59