Table 3.

Simulated power under the naïve Wald sample size $n_{\mathit{w}}$ for 95% VE at desired power 80% for the three tests. Wald test w. cc: Wald test with continuity correction. CCT: case-control study; TND: test-negative design.

Tests	Studies	Vaccine Coverage ($p_{\mathit{N}}$)
		10% ($n_{\mathit{w}}$=228)	30% ($n_{\mathit{w}}$=74)	50% ($n_{\mathit{w}}$=45)	70% ($n_{\mathit{w}}$=37)	90% ($n_{\mathit{w}}$=54)
Naïve Wald test	CCT	0.40	0.43	0.49	0.59	0.84
	TND	0.42	0.40	0.42	0.46	0.73
Wald test w. cc	CCT	0.42	0.47	0.61	0.74	0.89
	TND	0.37	0.40	0.45	0.52	0.77
Score test	CCT	0.88	0.86	0.83	0.83	0.86
	TND	0.86	0.83	0.79	0.76	0.82