Table 4.

Association analysis of ZNF592 and the C1 module.

Gene	Variants	Total MAC	Case MAC	Control MAC	Fraction Case	Fraction Control	OR (95% CI)	SKAT-O		Burden
								FDR	P	FDR	P
ZNF592	16	19	8	11	0.0023	0.0018	1.08 (1.01–1.16)	0.044	7.60×10−6	0.041	7.30×10−06
Module	Variants	Total MAC	Case MAC	Control MAC	Fraction Case	Fraction Control	OR (95% CI)	Permutation test	P	Permutation test	P
C1	180	234	101	133	0.029	0.022	1.31 (1.01–1.70)	0.19	0.048	0.078	0.006