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Association analysis of ZNF592 and the C1 module.
| Gene | Variants | Total MAC | Case MAC | Control MAC | Fraction Case | Fraction Control | OR (95% CI) | SKAT-O | Burden | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| FDR | P | FDR | P | ||||||||
| ZNF592 | 16 | 19 | 8 | 11 | 0.0023 | 0.0018 | 1.08 (1.01–1.16) | 0.044 | 7.60×10−6 | 0.041 | 7.30×10−06 |
| Module | Variants | Total MAC | Case MAC | Control MAC | Fraction Case | Fraction Control | OR (95% CI) | Permutation test | P | Permutation test | P |
| C1 | 180 | 234 | 101 | 133 | 0.029 | 0.022 | 1.31 (1.01–1.70) | 0.19 | 0.048 | 0.078 | 0.006 |
