. Author manuscript; available in PMC: 2024 Jan 17.

Published in final edited form as: Hum Immunol. 2019 May 20;80(9):731–738. doi: 10.1016/j.humimm.2019.04.020

Table 2.

Association between rs6906846 and the three most significantly associated HLA-C types (See Supplementary Table 2)

HLA-C type	US multi-ethnicity (Cohort 1)			Japanese (Cohort 2)			Combined
	rs6906846		p	rs6906846		p	p_combined
	A allele	G allele		A allele	G allele
	n=48	n=58		n=46	n=250
*04:01	20	0	8.6E-09	5	0	7.5E-05	1.1E-17
*07:02	23	0	2.8E-10	20	1	1.9E-17	2.8E-30
*12:02	0	0	NA	21	1	1.9E-18	NA

Bonferroni corrected p value threshold: 0.05/(50 HLA-B types + 26 HLA-C types)=6.6E-04, NA: not applicable, Only homozygous subjects of rs6906846 were included in the analysis.