Figure 3.

The effect of FMT on microbiota composition.

a: Average Bray-Curtis dissimilarity index between the non-relapsed FMT-treated patients and placebo groups compared to the donor. Non-relapsed FMT-treated patients had lower microbiota dissimilarity with the donor at week four (4 wk) than patients in the placebo group (p = .02, Wilcoxon signed rank test). b: Principal Coordinates Analysis (PCoA) plot for the non-relapsed FMT-treated patients and placebo groups at week four (4 wk), showing a grouping of some FMT-treated patients with the donor. c: Percentage of OTUs that were present in the donor’s and patients’ post-FMT sample but absent in the patients’ pre-FMT sample, indicating the donor-like OTUs appearing after baseline in the FMT group. d: PCoA plot for the four FMT-treated patients who did not relapse during the one-year follow-up. The microbiota composition of two patients showed a shift toward the donor microbiota. Non-relapsed (nr) and relapsed (r) patients.