Table 1.

Comparative effectiveness of different categories of interventions for depression.

The league tables show the pooled outcomes of the network meta-analyses (lower diagonal) and pairwise meta-analyses (upper diagonal) for comparative effectiveness of different categories of interventions for depression. The relative effect sizes of each approach were measured as a standardized mean difference and 95% CI. The bold indicates statistical significance. Comparisons between treatments should be read from left to right, and the estimate is in the cell in common between the column-defining treatment and the row-defining treatment. The imprecision for the rating of Certainty of Evidence on direct evidence was not considered. (According to the GRADE, recommended ‘consideration of imprecision is not necessary when rating the direct and indirect estimates to inform the rating of the network estimates’.) The detailed of Certainty of Evidence were presented in Appendices 7 and 9. BA, biopsychosocial approach; CO, control; EX, exercise; EDU, education; MBT, mind body therapy; MUI, multicomponent intervention; NA, not available; PT, physical therapy; TM, telemedicine. Interventions details are described in Appendix 3.