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. 2023 Sep 21;110(1):464–477. doi: 10.1097/JS9.0000000000000784

Table 4.

Summary of results from all subgroup analyses.

Indicators Subgrouped by The number of studies Effect size 95% CI I2 (%) P for between subgroup heterogeneity
Major complications Types of study 0.33
RCT 4 0.86 0.68, 1.09 56
MS 3 0.63 0.36, 1.11 0
Total biliary complications Types of study 0.61
RCT 5 0.71 0.54, 0.93 0
MS 6 0.79 0.58, 1.08 0
Donor type 0.99
DCD 4 0.74 0.59, 0.94 0
DBD 7 0.74 0.51, 1.08 0
HAT Types of study 0.46
RCT 4 1.18 0.38, 3.63 0
MS 2 0.54 0.09, 3.10 0
Donor type 0.53
DCD 3 0.70 0.19, 2.53 0
DBD 3 1.29 0.32, 5.13 21
NAS Types of study 0.92
RCT 2 0.35 0.14, 0.86 0
MS 5 0.33 0.15, 0.72 0
Donor type 0.28
DCD 4 0.29 0.15, 0.57 0
DBD 3 0.65 0.18, 2.32 0
PNF Types of study 0.59
RCT 4 0.40 0.10, 1.68 0
MS 6 0.67 0.22, 2.06 3
Donor type 0.30
DCD 4 0.26 0.05, 1.50 0
DBD 6 0.77 0.27, 2.21 0
EAD Types of study 0.41
RCT 5 0.50 0.38, 0.66 16
MS 5 0.62 0.41, 0.93 0
Donor type 0.67
DCD 3 0.58 0.38, 0.87 0
DBD 7 0.52 0.39, 0.69 23
Acute rejection Donor type 0.07
DCD 2 0.31 0.13, 0.75 68
DBD 3 0.90 0.43, 1.91 0
Patient survival Types of study 0.75
RCT 2 0.75 0.27, 2.07 0
MS 3 0.58 0.18, 1.93 0
Graft survival Types of study 0.92
RCT 3 0.37 0.16, 0.85 0
MS 4 0.39 0.17, 0.88 0
Donor type 0.33
DCD 2 0.23 0.07, 0.80 0
DBD 5 0.46 0.24, 0.90 0
Hospital stay Types of study 0.77
RCT 4 −1.54 −3.37, 0.30 67
MS 5 −1.06 −3.64, 1.53 0
Donor type 0.50
DCD 3 −1.94 −4.14, 0.27 0
DBD 6 −0.90 −2.94, 1.14 58
ICU stay Types of study 0.70
RCT 5 0.21 −0.19, 0.61 56
MS 4 −0.01 −1.07, 1.05 0
Donor type 0.17
DCD 3 0.55 −0.09, 1.19 0
DBD 6 −0.00 −0.46, 0.46 38
Renal replacement therapy Types of study 0.30
RCT 2 0.75 0.38, 1.47 0
MS 5 1.19 0.68, 2.08 1
Donor type 0.30
DCD 4 1.13 0.68, 1.89 27
DBD 3 0.68 0.31, 1.53 0

DBD, donors after brain death; DCD, donors after cardiac death; EAD, early allograft dysfunction; HAT, hepatic artery thrombosis; ICU, intensive care unit; MS, matched study; NAS, non-anastomotic biliary stricture; PNF, primary non-function; RCT, randomized controlled trial.