Skip to main content
. 2023 Oct 4;110(1):431–440. doi: 10.1097/JS9.0000000000000779

Table 2.

ICG and short-term (≤ 7 d) outcomes in liver transplants.

Study Study variable(s) Short-term outcome measure (n/N) Prognostic value analysis test Prognostic value for short-term outcome
Cherchi et al.28 Postoperative. ICG-PDR ≥16%/min on POD1 EAD (18/77) Univariate logistic regression model EAD: ICG-PDR OR 0.88 (0.79–0.97), P <0.01.
Yunhua et al.29 Preoperative. MELD score
Postoperative. ICG-R15 on 12 h post-LT		 EAD (25/61) Logistic regression EAD: MELD score (β=0.128, P=0.013), ICG-R15 (β=0.117, P=0.002).
Lock et al.32 Postoperative. ICG-PDR (%/min), AST (U/L), ALT (U/L), GLDH (U/L), Bilirubin (mg/dl), Ammonia (μmol/l), Albumin (g/dl), INR, Factor II (%), Factor VII (%) on POD 1 and 3 IDF (8a/99) Multivariate forward and backward logistic regression analysis IDF: ICG-PDR NS.
Tsubono et al.33 Postoperative. KICG-B, KICG-F, total bilirubin, highest PT. Graft loss (12a/50) Univariate and forward stepwise multivariate analysis Univariate analysis. Hepatic graft loss: KICG-B on POD1,3,7, KICG-F on POD1,3,7, total bilirubin on POD 3,7, highest PT. P <0.01
multivariate analysis. Hepatic graft loss: KICG-B on POD1, P=0.0003; highest PT, P=0.0815
a

8: 3 cases of re-transplantation on postoperative days (PODs) 4–6 due to primary non-function (PNF), 5 cases of surgical reintervention on postoperative day (POD) 1 due to severe anastomotic bleeding, Hepatic artery thrombosis (HAT), or portal vein thrombosis.

ALT, alanine aminotransferase; AST, aspartate aminotransferase; EAD, early graft dysfunction; GLDH, glutamate dehydrogenase; ICG-PDR, indocyanine green plasma disappearance rate; ICG-R15, ICG retention rate at 15 minutes; IDF, initial graft dysfunction; INR, international normalized ratio; KICG-B, measurement by spectrophotometric method; KICG-F, measurement by finger-piece method; MELD, Model for End-Stage Liver Disease; NS, Not Statistically Significant; OR, odd ratio; POD, postoperative day; PT, prothrombin time.

12: 7 cases of re-transplantation or death due to hepatic causes and 5 cases of re-transplantation or death for technical or extrahepatic reasons.