Fig. 2. Stress test simulation results for the oxycodone distribution system in 2012.

(A) Percentage of final buyers’ total demand that was not met, shown as the deficit, for reroute flexibility values ϕ ∈ [0,1]. The results are plotted at 40, 50, and 60 days after production stopped. The reroute flexibility value ϕ^* yielding the maximum deficit reduction is shown in red. (B) Available resupply window shown as the time available to resupply before breaching a CSD, black line. The extended resupply window obtained with ϕ = ϕ^*, shown in red, is always above the black line. The resupply window obtained with full flexibility (ϕ = 1) is shown as the dashed line. Up to point q, the resupply window is the same for ϕ = 0 and ϕ^*. Beyond point r, the largest resupply window is obtained for ϕ^* < 1. Beyond point s, full flexibility (ϕ = 1) is worse than no flexibility (ϕ = 0). (C) Time gained with flexibility, showing the increase in the time available for resupply for a given CSD.