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Competitive antagonist activity of adenosine 3′-phosphate 5′-phosphosulfate. Turkey erythrocyte membranes were incubated in the presence of the indicated concentrations of adenosine 3′-phosphate 5′-phosphosulfate and no additional drug (open circles), 10 nM 2MeSATP (filled circles), or 100 nM 2MeSATP (open squares). Inositol phosphate accumulation was measured as a quantitation of PLC activity.
