Fig. 2.

Six subcategories of the modified Sarnat staging at randomisation indicating the level of abnormality within each subcategory in long birth depression and short birth depression groups is shown in the top panel. The term LOC indicates level of consciousness and ANS indicates autonomic nervous system. Infants only qualified for cooling if they had at least 3 of the 6 subcategories classified as moderate or severe at randomisation. Progression of encephalopathy stage during neonatal hospitalisation in long birth depression and short birth depression groups is shown in bottom left panel, and the median (IQR) of age of seizure onset in the bottom right panel (five outliers with seizure onset above 36 h were excluded from the plot).