Extended Data Table 2.

MIC of RO7075573 versus efflux impaired and porin deficient strains of E. coli, K. pneumoniae and P. aeruginosa

MIC broth microdilution conducted in CAMHB, read at 100% bacterial growth inhibition. acrA/B, acriflavine resistance protein A/B; mexA/B/C/D/E/F/J/K, multidrug efflux protein A/B/C/D/E/F/J/K; ompC/F, outer membrane porin protein C/F; opmH, outer membrane protein M family protein H; oprD/J/M/N, outer membrane porin protein D/J/M/N; tolC, colicin tolerance protein; WT/wt, wild-type.