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. 2024 Jan 17;10:3. doi: 10.1038/s41522-024-00476-x

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — A RNA-seq detected 2,949 genes were categorized by hierarchical clustering approach (n = 6). B Subcluster analysis were further performed to determine the trends in gene expressions among groups. C Volcano plot revealed 2,084 DEGs (1185 up-regulated and 899 down-regulated) between the control group and the nisin group (left panel) and 560 DEGs (408 up-regulated and 152 down-regulated) between the infection group and the inf. + nisin group (right panel).