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. 2024 Jan 17;32(2):109. doi: 10.1007/s00520-024-08308-6

Table 2.

Outcomes regarding feasibility of tools supporting communication about intimacy and sexuality

First author, year Tool (model, programme, intervention, components, duration) Willingness to participate, including eligible and participating participants Lost to follow-up, including compliance with programme Usability MMAT1
Akeflo, 2022 [38]

PLISSIT2

Nurse-led intervention with visits and/or phone calls or digital meetings, applied 3 months to several years (individualized care)

975 eligible participants of which 605 took part in baseline questionnaire (62.1%)

605 participants were included of which 379 (62.6%) approved to take part in the intervention

605 participant took part in baseline questionnaire of which 226 (37.4%) were lost to follow-up before the intervention

379 participants took part in the intervention of which 119 (31.4%) were lost to follow-up

In total 345 out of 605 participants (57.0%) were lost to follow up

88.6% of the participants reported that they were moderately to very satisfied with the help offered regarding sexual health issues *
De Almeida, 2020 [39]

PLISSIT counselling, five weekly sessions of 1.5 h each

Control group received one lecture (2 h)

40 eligible patients of which 23 agreed to participate (57.5%) 23 patients included in study of which 5 were lost to follow-up, all from intervention group (21.7%) ***
Bingham, 2022 [40] Engagement, Assessment, Support and Signposting (EASSi) framework, one-time training (eLearning), duration approximately 1 h

157 participants included in study of which 68 were lost to follow-up (43.3%, calculated upon post-test survey participation)

89 participants completed the study of which 2 did not fully comply with the intervention (2.4%)

Intervention considered easy to use by HCPs3 **
Bokaie, 2022 [41] Problem-solving approach (sessions), counselling, eight weekly sessions, 90 min per session

100% participation rate

None of the patients wanted to be in control group

***
Bokaie, 2023 [42]

Solution-focused approach, online counselling, eight weekly sessions, 90 min per session

Control group: educational pamphlet to read every 3 weeks

165 eligible participants of which 80 agreed to participate (48.5%) 80 participants included in study of which 15 were lost to follow-up (18.8%) ***
Chambers, 2014 [43]

DVD and tip sheet and sessions, counselling,

six–eight telephone sessions delivered by nurses (intervention 1) or by peers (intervention 2)

405 eligible participants of which 189 agreed to participate (46.7%) 189 participants included in study of which 30 were lost to follow-up or did not comply (15.9%) Duration of sessions longer in the nurse group (36 min) as compared to the peer group (29 min) (p4 < .001) **
Chow, 2014 [44]

Structured sessions, psycho-educational intervention programme, three individual sessions and one group session

Control group received attention on 4 occasions

30 eligible participants of which 26 agreed to participate (86.7%)

26 participants included in study of which 2 were lost to follow-up (3.9%)

Intervention: 13 participants included of which 4 did not fully comply (30.7%); Control: 13 participants included of which 7 did not receive all attention (53.8%)

Intervention considered appropriate (time, frequency and provider) by patients

Considered practical and feasible by nurses

**
Cullen, 2021 [45] Online couple-based psychosexual intervention, six sessions 25 eligible couples of which 18 agreed to participate (72%) 18 couples included in study of which 3 did not comply with the intervention programme (16.7%) **
Du, 2020 [46] Group intervention with education sessions, seven sessions of at least 30 min **
DuHamel, 2016 [47]

Sessions and booster call, educational intervention, four sessions of 1 h, booster call between sessions

Control group: no calls

82/204 (40%) eligible patients participated

204 eligible participants of which 82 agreed to participate (40%)

In total 82 participants included in study of which 9 were lost to follow-up; Intervention: 40 participants included of which 6 were lost to follow-up (15.0%); control: 42 participants of which 3 were lost to follow up (7.1%)

Compliance with programme, 96% HCPs (manual), 89% patients (homework)

*
El- Sayed Saboula, 2015 [48] PLISSIT counselling, six sessions lasting 2 h each during 3 weeks 85 participants included in study of which 19 were lost to follow-up (22.3%) **
Esmkhani, 2021 [49]

PLISSIT (individual) and Sexual Health Model [SHM] (group), counselling, one–three sessions of 40–60 min (individual), 6-h workshop (group)

Control group received usual care

395 eligible participants of which 75 agreed to participate (19%) In total 75 participants included in study of which 10 were lost to follow-up (13.3%); Individuals: 25 participants of which 3 were lost to follow-up (12.0%); Group: 25 participants of which 0 were lost to follow-up; Control: 25 participants of which 7 were lost to follow-up (28.0%) **
Faghani, 2016 [50]

PLISSIT counselling, 4 × 90-min sessions

Control group: no intervention

***
Fatehi et al., 2019 [51]

Schover’s sexual assessment method,

psychosexual counselling, six weekly sessions of 90–120 min

289 eligible participants of which 118 agreed to participate (40.8%) In total 118 participants included in study of which 18 were lost to follow-up or excluded from study (15.2%); Intervention: 59 participants of which 8 lost to follow-up (13.6%); Control: 59 participants of which 10 lost to follow-up (16.9%) ****
Jonsdottir, 2021 [52] Couple based Strengths-Oriented Therapeutic Conversation (CO-SOTC), three sessions of 45 min 149 eligible couples of which 60 agreed to participate (49% acceptance rate) 60 couples included in study of which 1 withdrew after randomization (1.7%) ***
Jonsdottir, 2021 [53] Couple based Strengths-Oriented Therapeutic Conversation (CO-SOTC), three sessions of 45 min 149 eligible couples of which 60 agreed to participate (49% acceptance rate) 60 couples included in study of which 1 withdrew after randomization (1.7%) ***
Keshavarz, 2021 [54]

PLISSIT

counselling, seven sessions of 60 min for 4 weeks

88 eligible participants of which 67 agreed to participate (76.1%)

2/67 (3.0%) were lost to follow-up

67 participants included in study of which 2 were lost to follow-up (3.0%)

***
Khoei, 2022 [55]

PLISSIT (individual) and Grouped Sexuality Education (group)

counselling, one–three sessions of 40–60 min (individual) or 6-h workshop (group)

395 eligible participants of which 75 agreed to participate (19.0%) In total 75 participants included in study of which 10 were lost to follow-up (13.3%); Individuals: 25 participants of which 3 were lost to follow-up (12.0%); Group: 25 participants of which 0 were lost to follow-up; Control: 25 participants of which 7 were lost to follow-up (28.0%)
Li, 2023 [56]

Systematic Transactional Model of Stress and Coping;

psychosocial intervention programme (WeChat), 8-week programme

Control group: six articles received over an 8-week period

185 eligible patient-partner dyads of which 98 couples agreed to participate (53%)

98 patients included in study of which 26 were lost to follow-up (26.5%); Intervention: 49 patients of which 14 were lost to follow-up (28.6%); Control: 49 patients of which 12 were lost to follow-up (24.5%)

98 partner included in study of which 29 were lost to follow-up (29.6%); Intervention: 49 partners of which 14 were lost to follow-up (28.6%); Control: 49 partners of which 15 were lost to follow-up (30.6%)

**
Maughan, 2001 [57]

Information, advice and support, psychosexual intervention by Clinical Nurse Specialist, with visit prior to surgery and home visits (3 on average)

Control group had no visits

Acceptance rate 100% *
McCaughan, 2020 [19]

EASSi5 framework (Tablet-based)

Training (e-learning) of 30 min to use tool

HCPs viewed the EASSi tool as feasible, acceptable, appropriate

HCPs deemed EASSi unsuitable for patient who is medically unstable, for patient who is attending with a family member (other than partner), or who is ‘not concerned’ about sexual issues

**
McCaughan, 2021 [58] EASSi framework, brief e-learning consisting of three sections HCPs viewed tool as easy to use *
Mohammadi, 2022 [59]

EX-PLISSIT6, Counselling, 4 weekly sessions lasting 60–90 min

Control group: one online session

122 eligible participants of which 110 agreed to participate (90.2%) 110 participants included in study of which 11 were lost to follow-up (10.0%) ****
Olcer, 2022 [60]

BETTER7

Counselling, four sessions with 1-week interval

116 eligible participants of which 77 agreed to participate (66.4%) 77 participants included in study of which 12 were lost to follow-up (15.6%); Intervention: 38 participants of which 5 were lost to follow-up (13.2%); Control: 39 participants of which 7 were lost to follow-up (17.9%) *****
Perz, 2015 [61]

PLISSIT

Self-help booklet consisting of 68 pages providing self-help information (group) or information and 1-h telephone consultation (group 2)

394 eligible patients of which 88 agreed to participate (22.3%);

122 eligible partners of which 53 agreed to participate (43.4%)

In total 88 patients included in study of which 29 were lost to follow-up (32.9%); Group 1: 45 patients included of which 12 were lost to follow-up (26.7%); Group 2: 43 patients included of which 17 were lost to follow-up (39.5%)

In total 53 partners included in study of which 22 were lost to follow-up (41.5%); Group 1: 25 partners of which 7 were lost to follow-up (28.0%); Group 2: 28 partners of which 15 were lost to follow-up (53.6%)

Self-help booklet and Health professional information were rated as useful in helping to manage changes to sexuality and talking with their partner about sexuality Self-help booklet was rated favourably *
Reese, 2012 [62]

Intimacy Enhancement Intervention,

Counselling, four phone-based sessions of 50 min

34 couples invited to participate of which 14 agreed to participate (41.2%) 14 couples included in study of which 5 were lost to follow-up of did not complete intervention (35.7%) 83% of patients perceived the programme as easy to participate in and helpful in communication and behavioural skills **
Reese, 2019 [34]

PLISSIT

Training to equip clinicians for counselling, two modules (15 and 60 min)

Eight eligible clinicians of which 7 participated (87.5%); 172 approached patients of which 137 agreed to participate (79.9%) All clinicians completed the intervention; 137 patients included in study of which 3 were lost to follow-up (2.2%) Clinicians’ responses on post intervention programme evaluation: The results suggested intervention feasibility *
Reese, 2021 [63] Starting the Conversation, Online patient training including video slideshow (20 min) and five-page workbook 177 eligible participants of which 144 agreed to participate (81.4%) In total 144 participants included in study of which 22 were lost to follow-up or did not fully comply to intervention (15.2%) ***
Reese, 2023 [64] Starting the Conversation, educational intervention for patients including video slideshow (23 min) and five-page workbook 42 eligible participants of which 32 agreed to participate (76.2%) 32 participants included in study of which 1 was lost to follow-up (3.1%) ***
Roberts, 2020 [65] Brief sexual symptom checklist for women applied in routine care **
Shalamzari, 2022 [66] PLISSIT and BETTER-model, Counselling, four sessions of 60–90 min with 1-week interval 78 participants included in study of which 2 were lost to follow-up (2.6%) ****
Taleb, 2023 [67] Structured sessions, nursing intervention consisting of five sessions ***
Wang, 2022 [68] EX-PLISSIT applied in training for HCPs8 -
Winterling, 2020 [23] Fex-talk, Educational intervention, single session lasting 2 h, optional second session Fex-Talk intervention was experienced positively by the participating nurses, seemed to increase awareness and appeared to boost confidence to initiate discussions **
Zhang, 2022[69] Structured sessions, Nurse led intervention, monthly sessions of 4 h, lasting for three consecutive treatment cycles 120 eligible couples of which 106 agreed to participate (88.3%) In total 106 couples included in study of which 11 were lost to follow-up (10.4%); Intervention: 53 couples of which 7 were lost to follow-up (13.2%); Control: 53 couples of which 4 were lost to follow-up (13.2%) *****

Abbreviations:

1MMAT Mixed Methods Appraisal Tool

2PLISSIT Permission, Limited Information, Specific Suggestions, Intensive Therapy

3HCPs Healthcare Professionals

4P P-value

5EASSI Engagement, Assessment, Support and Signposting

6EX-PLISSIT Extended-PLISSIT

7BETTER Bring up the topic, Explain, Telling, Timing, Education, Recording

8HCPs Healthcare professionals