Table 3.
MVMR analysis results of gut microbiota and autoimmune hypothyroidism.
| Gut microbiota | Methods | OR | CILower | CIUpper | P |
|---|---|---|---|---|---|
| Family.Defluviitaleaceae | IVW | 0.158 | 0.027 | 0.928 | 0.041 |
| Family.Defluviitaleaceae | Median | 0.190 | 0.156 | 0.230 | 0.000 |
| Family.Defluviitaleaceae | MR-Egger | 0.138 | 0.024 | 0.802 | 0.027 |
| Genus.DefluviitaleaceaeUCG011 | IVW | 0.164 | 0.028 | 0.967 | 0.046 |
| Genus.DefluviitaleaceaeUCG011 | Median | 0.194 | 0.160 | 0.235 | 0.000 |
| Genus.DefluviitaleaceaeUCG011 | MR-Egger | 0.149 | 0.026 | 0.868 | 0.034 |
| Genus.Eggerthella | IVW | 0.967 | 0.909 | 1.028 | 0.279 |
| Genus.Eggerthella | Median | 0.931 | 0.861 | 1.007 | 0.076 |
| Genus.Eggerthella | MR-Egger | 0.971 | 0.914 | 1.033 | 0.356 |
| Genus.Intestinimonas | IVW | 0.986 | 0.939 | 1.036 | 0.577 |
| Genus.Intestinimonas | Median | 0.964 | 0.899 | 1.033 | 0.298 |
| Genus.Intestinimonas | MR-Egger | 0.982 | 0.935 | 1.031 | 0.470 |
| Genus.RuminococcaceaeUCG011 | IVW | 0.997 | 0.946 | 1.050 | 0.899 |
| Genus.RuminococcaceaeUCG011 | Median | 1.025 | 0.958 | 1.097 | 0.478 |
| Genus.RuminococcaceaeUCG011 | MR-Egger | 0.997 | 0.946 | 1.050 | 0.899 |
| Genus.Subdoligranulum | IVW | 0.979 | 0.911 | 1.052 | 0.569 |
| Genus.Subdoligranulum | Median | 0.974 | 0.882 | 1.077 | 0.614 |
| Genus.Subdoligranulum | MR-Egger | 0.984 | 0.916 | 1.058 | 0.664 |
| Phylum.Actinobacteria | IVW | 0.933 | 0.848 | 1.027 | 0.159 |
| Phylum.Actinobacteria | Median | 0.946 | 0.829 | 1.079 | 0.409 |
| Phylum.Actinobacteria | MR-Egger | 0.934 | 0.850 | 1.027 | 0.162 |