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. 2024 Jan 4;11:1327426. doi: 10.3389/fchem.2023.1327426

TABLE 5.

Applications of chitosan derivatives and chitosan-based nanocomposites in cosmetics.

Systems Main findings References
Carboxymethyl chitosan A remarkable moisturizing effect due to the polymer’s ability to form a hydrated layer on the skin’s surface, preventing water loss Chaiwong et al. (2020)
Chitosan-lemongrass essential oil films Application as antioxidant and antimicrobial care masks with high flexibility and permeability, without cytotoxic risks Gaspar et al. (2022)
Methylcellulose-chitosan smart gels Heat protection with chitosan that acts like a film on the hair, protecting it from heat damage. Applied like an ultra-hold hairspray on hair, it fixes the style for hours Hartson et al. (2022)
Carboxymethyl chitosan Safety and efficacy of injectable soft tissue devices for the intradermal treatment of age-related skin defects. Significant improvement in skin hydration, firmness, and elasticity Philippart et al. (2021)
Thymoquinone-loaded chitosan nanoparticles Superior antimicrobial activity over time and a natural, effective, and lasting preservative effect in cosmetic products Mondéjar-López et al. (2022)
Pomegranate juice-loaded chitosan derivative nanoparticles Improved antioxidant and antimicrobial properties of skin emulsions with good storage stability. Higher sun protection factor Bikiaris et al. (2020)
Carboxymethyl chitosan-mangosteen extract Good moisturizing power for the skin and good deodorizing property against trans-2-nonenal odor, with antioxidant and antibacterial properties Chaiwong et al. (2022)
Chitosan nanoparticles A significant anti-sebum characteristic on the T-zone of the face after 4 weeks, without significant disruption of the skin barrier Theerawattanawit et al. (2022)
N-[(2-hydroxy-3-trimethyl-ammonium)-propyl] chitosan chloride Excellent antibacterial and mechanical properties, with desirable cell attachment and proliferation Khalaji et al. (2021)
Chitosan/vitamin C complex Enhanced antioxidant, moisturizing, antibacterial, and film-forming properties. High moisture retention, hygroscopicity, ability to scavenge hydroxyl radicals, and high stability Liping et al. (2020)