Figure 1.

Pipeline for the construction of myelin-weighted brain graphs. We combined the myelin-sensitive MVF map with streamlines reconstructed from the diffusion image using two methods. Tractometry, which samples each streamline at n points to which it assigns the voxel-wise value of the underlying microstructural map and computes the average, and MySD, which solves a linear system for each voxel of the microstructural map by assigning a contribution to each streamline relative to the scalar value measured in the map. We used the same procedures to reconstruct the diffusion-weighted brain graph using INVF scalar map. MTsat, Magnetization Transfer saturation; DWI, Diffusion Weighted Image; MVF, Myelin Volume Fraction; INVF, intra-neurite volume fraction.