TABLE 5.

Binding affinities between Orobanche foetida compounds and PAR-1, TNF-α and IL-6.

Compounds	Binding affinity (kcal/mol)
	PARP-1	TNF-α	IL-6
Malic acid	−4.4	−4.6	−4.1
Dihydroxybenzoic acid	−9.1	−6.3	−5.1
Caffeic acid	−7.2	−7.1	−5.1
Quinic acid	−6.2	−6.4	−4.7
Homovanillic acid malate	−6.4	−6.7	−4.9
Dihydroxybenzoic acid glucoside	−8.3	−7.2	−5.7
Coumaroyl glucose	−9.0	−9.3	−5.6
Vanillic acid glucoside	−8.4	−7.6	−5.3
Coumaroyl quinic acid	−6.9	−8.8	−5.8
Caffeoyl glucose	−9.4	−9.3	−5.7
Sinapoyl glucose	−8.9	−8.1	−5.6
Isorhamnetin glucoside	−10.4	−8.6	−5.6
Caffeic acid pentosyl glucuronide	−9.0	−8.5	−5.8
Silymarin(R)	−11.7	−8.7	−7.4

(R): reference, drug.