TABLE 1.

Size, polydispersity indices and encapsulation efficiency of the chitosan nano-capsules.

Samples	Size distribution (NM)	Average size (NM)	Polydispersity index (PDI)	ZP (MV)	Encapsulation efficiency (%)
CNP	69–361	165 ± 2	0.1 ± 0	+25	-
CNP-NQ1	80–420	193 ± 2	0.1 ± 0	+31	98
CNP-NQ2	64–568	193 ± 9	0.1 ± 0	+33	96

All experiments were performed in triplicate and the means and standard deviation were calculated (Taylor, 1997). Average sizes and polidispersity indices (PdI) were determined by dynamic light scattering (DLS) and Z potentials (ZP) was determined by electrophoretic light scattering (ELS). Encapsulation efficiency (EE) was calculated as described in Eq. 1 where the CNP-loaded naphtoquinones were determined by quantifying free naphthoquinone in the supernatants: EE (%) = C_{(NQ, added)}—C_{(NQ, unencapsulated)}/C_{(NQ, added)} X 100. NQ1—3-chloromethylene-menadione; NQ2—2,3-dichloro-1, 4-naphthoquinone; CNP, chitosan nanocapsule; CNP-NQ1, chitosan nanocapsules containing NQ1; CNP-NQ2, chitosan nanocapsules containing NQ2.