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. 2024 Jan 4;13:1257120. doi: 10.3389/fonc.2023.1257120

Table 2.

The clinical parameter META analysis.

Clinicopathological parameters Studies (n) Patients (n) OR (95%CI) P I2 PQ Model Pegger
TNM stage (III+IV vs. I+II) 4 338 2.93 (1.80-4.77) <0.001 70.00% 0.018 Random 0.282
Tumor invasion 5 488 2.90 (1.90-4.41) <0.001 75.90% 0.002 Random 0.469
Lymph node metastasis (positive vs. negative) 5 488 2.99 (1.97-4.54) <0.001 28.30% 0.233 Fixed 0.918
Distant metastasis (presence vs. absence) 3 292 3.11 (1.68-5.75) <0.001 92.80% <0.001 Random 0.509
Histologic grade (poor vs. well, moderate) 3 288 1.00 (0.46-2.20) 0.997 0.00% 0.864 Fixed 0.084