Fluorescent probes for the detection of β-galactosidase in ovarian cancer cells.

Name of the probe	λ ex/λem (nm)	Detection approach	Cells	Cytotoxicity	Quantum yield	LOD	Ref.
β-CD-CQDs	420/570	Turn on	OVCAR-3 cells	200 μg mL−1	0.02	0.6 U L−1	61
CG	370/475	Ratiometric	—	5 mg mL−1	0.95	0.081 U mL−1	63
DCM-β-gal-UCNPs	543/800	Ratiometric	SKOV-3, 293 T and zebrafish	1 mg mL−1	—	3.1 × 10−4 U mL−1	64
Cyclometalated iridium(iii) complexes	282/550	Turn on	Ovarian carcinoma cell and normal cell	79.4 and 63.1 μM	—	0.51 U mL−1	65
GNPN	475/545	Ratiometric	MDBK and OVCAR-3 cells	80 mM	0.17	0.17 U L−1	66
MC-βGal	493/554	Turn on	OVCAR-3 and HeLa cells	100 μM	—	0.019 U mL−1	67
TMG	580/650	Turn on	MDBK and OVCAR-3 cells	5 mg mL−1	—	0.86 U L−1	68
FLM	450/550	Ratiometric	MDBK and OVCAR-3 cells	5 mg mL−1	0.36	0.19 U L−1	69
DMC-βgal	725/770	Turn on	SKOV-3 cells	10 μM	—	0.298 U L−1	71
DCM-CHO-βgal	525/665	Turn on	HepG2 and SKOV-3 cells	10 μM	0.07	3.15 × 10−5 U mL−1	73
AM-RP-G	490/530	Ratiometric	SKOV-3 cells	10 mg mL−1	—	1.4 × 10−3 U mL−1	74
ESIPT-GAL	406/502	Turn on	HeLa and OVCAR-3 cells	30 μM	0.0045	3.9 × 10−5 U mL−1	82
ESIPT-GAL	452/526	Turn on	SKOV-3 cell	—	—	1.26 × 10−3 U mL−1	83
TZ-Br	405/670	Ratiometric	OVCAR-3 cells	30 μM	0.17 in PBS	1.9 × 10−3 U mL−1	84
QM-βgal	355/434	Turn on	SKOV-3 cells	10 μM	0.005	1.0 × 10−3 U mL−1	85
BOD-M-βgal	533/565	Turn on	SKOV-3 cells	100 μM	—	—	86
HBTTPAG	488/574	Turn on	SKOV-3 cells	20 μM	0.54	3.7 × 10−3 U mL−1	87
CCGal1	620/662	Turn on	SKOV-3 cells	20 μM	0.18	0.24 U mL−1	93
Lyso-gal	533/565	Turn on	SKOV-3 cells	50 μM	< 0.1%	0.022 U mL−1	98
HMRef-βGal	600/725	Ratiometric	SKOV-3 cells	100 μM	—	—	99
DXM-βgal	570/764	Ratiometric	OVCAR 3 cells	30 μM	0.16	6.7 × 10−3 U mL−1	107
DXM-βgal	520/605	Turn on	SKOV-3 cells	10 μM	—	2.92 × 10−4 U mL−1	108
Gal-Br-NO2	415/670	Turn on	MDBK, HeLa, and OVCAR-3 cells	30 μM	0.32	0.0035 U mL−1	109