Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Evolution of the conformational ensemble of p53-NTD at 298 K during (A) REST2, (B) REST3 (16-replica), and (C) REST3 (8-replica) folding simulations in a99SB-disp. The ensembles were projected along the same first two principal components derived from PCA analysis of all conformations sampled from REST2 and REST3 runs. All probability distributions were first converted into free energy surface before plotting.
