TABLE 2.
Subgroup | No. | AHA BP target | p‐value | China BP target | p‐value | BP response | p‐value |
---|---|---|---|---|---|---|---|
Age, n (%) | .031 | .062 | .002 | ||||
<65 years | 847 | 292 (34.5) | 729 (86.1) | 750 (88.5) | |||
⩾65 years | 436 | 177 (40.6) | 358 (82.1) | 359 (82.3) | |||
Sex, n (%) | .000 | .005 | .017 | ||||
Female | 539 | 243 (45.1) | 474 (87.9) | 480 (89.0) | |||
Male | 745 | 226 (30.3) | 613 (82.3) | 629 (84.4) | |||
BMI, n (%) | .024 | .043 | .067 | ||||
<30 kg/m2 | 1129 | 412 (36.4) | 935 (82.8) | 952 (84.3) | |||
⩾30 kg/m2 | 155 | 32 (20.6) | 92 (59.3) | 95 (61.2) | |||
Education level, n (%) | .234 | .455 | .652 | ||||
Primary school or less | 126 | 53 (42.1) | 102 (81.0) | 106 (84.1) | |||
High school | 583 | 201 (34.5) | 494 (84.7) | 502 (86.1) | |||
Undergraduate or above | 575 | 215 (37.4) | 491 (85.4) | 501 (87.1) | |||
Smoker, n (%) | .000 | .000 | .001 | ||||
No | 885 | 353 (39.9) | 771 (87.1) | 784 (88.5) | |||
Yes | 399 | 116 (29.1) | 316 (79.2) | 325 (81.4) | |||
Alcohol intake, n (%) | .008 | .005 | .012 | ||||
No | 1055 | 403 (38.2) | 907 (86.0) | 923 (87.4) | |||
Yes | 229 | 66 (28.8) | 180 (78.6) | 186 (81.2) | |||
Hypertension duration, n (%) | .015 | .090 | .001 | ||||
< 5 years | 539 | 220 (40.8) | 470 (87.2) | 487 (90.3) | |||
5−9 years | 227 | 82 (36.1) | 190 (83.7) | 193 (85.0) | |||
≥10 years | 518 | 167 (32.2) | 427 (82.4) | 429 (82.8) | |||
Family history of hypertension, n (%) | .447 | .320 | .588 | ||||
No | 475 | 178 (37.5) | 408 (85.9) | 413 (86.9) | |||
Yes | 778 | 275(35.3) | 652 (83.8) | 668 (85.8) | |||
History of allergy, n (%) | .285 | .466 | .767 | ||||
No | 1141 | 423 (37.1) | 967 (84.8) | 985 (86.3) | |||
Yes | 130 | 42 (32.3) | 107 (82.3) | 111 (85.3) | |||
History of respiratory disease, n (%) | .675 | .277 | .440 | ||||
No | 1180 | 428 (36.3) | 1002 (84.9) | 1022 (86.6) | |||
Yes | 99 | 38 (38.4) | 80 (80.8) | 83 (83.8) | |||
History of kidney disease, n (%) | .976 | .089 | .272 | ||||
No | 1215 | 444 (36.5) | 1033 (85.0) | 1052 (86.5) | |||
Yes | 66 | 24 (36.4) | 51 (77.3) | 54 (81.8) | |||
History of diabetes, n (%) | .261 | .127 | .401 | ||||
No | 1072 | 398 (37.1) | 914 (85.3) | 929 (86.6) | |||
Yes | 206 | 68 (33.0) | 167 (81.1) | 174 (84.4) | |||
History of CCVD, n (%) | .984 | .073 | .039 | ||||
No | 934 | 341 (36.5) | 801 (85.8) | 818 (87.5) | |||
Yes | 350 | 128 (36.6) | 286 (81.7) | 291 (83.1) | |||
History of dyslipidemia, n (%) | .024 | .391 | .560 | ||||
No | 757 | 259 (34.2) | 649 (85.7) | 658 (86.9) | |||
Yes | 499 | 202 (40.5) | 419 (84.0) | 428 (85.7) | |||
Respiratory rate, n (%) | .000 | .620 | .487 | ||||
Normal | 637 | 285 (44.7) | 912 (43.1) | 931 (46.1) | |||
Abnormal | 647 | 184 (28.4) | 9 (1.3) | 9 (1.3) | |||
Heart rate, n (%) | .340 | .401 | .224 | ||||
Normal | 1199 | 427 (35.6) | 990 (82.5) | 1010 (84.2) | |||
Abnormal | 85 | 25 (29.4) | 47 (55.2) | 47 (55.2) | |||
SeSBP, n (%) | .000 | .000 | .000 | ||||
Normal | 637 | 285 (44.7) | 591 (92.8) | 578 (90.7) | |||
Abnormal | 647 | 184 (28.4) | 496 (76.7) | 531 (82.0) | |||
SeDBP, n (%) | .000 | .000 | .126 | ||||
Normal | 772 | 326 (42.2) | 686 (88.9) | 676 (87.5) | |||
Abnormal | 512 | 143 (27.9) | 401 (78.3) | 433 (84.5) | |||
Hypertension severity class, n (%) | .000 | .000 | .000 | ||||
Mild | 502 | 243 (48.4) | 440 (87.6) | 446 (88.8) | |||
Moderate or severe | 782 | 214 (27.3) | 616 (78.8) | 616 (78.8) | |||
History of hypertension treatment, n (%) | .342 | .630 | .324 | ||||
Ever treatment | 1162 | 422 (36.3) | 958 (82.4) | 978 (84.1) | |||
First treatment | 122 | 38 (31.1) | 96 (78.6) | 96 (78.6) | |||
History of antihypertensive drugs, n (%) | .293 | .079 | .001 | ||||
Monotherapy | 709 | 270 (38.1) | 617 (87.0) | 631 (88.9) | |||
Double combination | 374 | 134 (35.8) | 309 (82.6) | 312 (83.4) | |||
Triple combination | 72 | 21 (29.2) | 58 (80.6) | 54 (75.) | |||
Combinations, n (%) | .113 | <.001 | <.001 | ||||
No combination | 1024 | 380 (37.1) | 866 (84.5) | 881 (86.0) | |||
Lipid‐modifying drug | 112 | 39 (34.8) | 85 (75.8) | 87 (77.6) | |||
Lipid‐modifying drug and others | 148 | 41 (27.7) | 103 (69.5) | 106 (71.6) |
Abbreviations: AHA, American Heart Association; BMI, body mass index; BP, blood pressure; CCVD, cardiovascular and cerebrovascular diseases; SeSBP, seated systolic blood pressure; SeDBP, seated diastolic blood pressure; W8, week 8.
The bold value indicate P‐value of statistical significance.