Figure 5.

This diagram demonstrates the specific gene expression changes identified in this study. The genes are separated by effect/pathway and treatment type, with green indicating pro-immunogenic or pro-apoptotic genes, and red indicating genes that are anti-immunogenic or anti-apoptotic. The plus signs (+) corresponds to the level of increased gene expression, as compared to control. It is important to note that the combination of hypofractionated radiation therapy with magnetic nanoparticle hyperthermia led to greater changes in both Natural Killer cell and T cell activation/cytotoxicity, as well as apoptosis.