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. 2024 Jan 18;13:35. doi: 10.1186/s13643-023-02382-3

Table 3.

Included studies which reported access to treatment defined as treatment receipt and utilisation (n = 15)

Author (year) Outcome of interest Type of SACT treatment Main finding(s)
Accordino et al. (2017) [26] Receipt of EOL care which included receipt of IV chemotherapy within the last 14 days of life IV chemotherapy as treatment within the last 14 days of life 60% receipt of IV chemotherapy as treatment within the last 14 days of life
Alves et al. (2022) [33] Receipt of no SACT treatment Unspecified SACT 60% of women received no first-course treatment
Cole et al. (2019) [34] Receipt of specialist palliative care (SPC) which included non-curative systemic chemotherapy Non-curative systemic chemotherapy 18.5% received specialist palliative care (SPC) which included non-curative systemic chemotherapy
Falchook et al. (2017) [35] Receipt of chemotherapy within the last 14 days of life Chemotherapy within the last 14 days of life 14.1% received chemotherapy within the last 14 days of life
Giap et al. (2023) [27] Receipt of palliative care which included non-curative systemic therapy Non-curative systemic chemotherapy 21.4% received non-curative systemic chemotherapy
Sathe et al. (2023) [28] Receipt of cyclin-dependent kinase 4 and 6 (CDK4 and CDK6) inhibitors following secondary (metastatic) breast cancer diagnosis Cyclin-dependent kinase 4 and 6 (CDK4 and CDK6) inhibitors 76.3% received CDK4/6i
Shih et al. (2009) [39] Receipt of immunotherapy post diagnosis Immunotherapy 4% received immunotherapy post diagnosis
Shiovitz et al. (2015) [40] Utilisation of cancer-directed therapy which included chemotherapy Chemotherapy 61% received SACT
Skinner et al. (2021) [32] Receipt of systemic anticancer therapy Unspecified SACT 83% received SACT
Small et al. (2012) [41] Receipt of no first course anticancer therapy Unspecified SACT—no first-course therapy 12.8% received no first-course SACT therapy
Statler et al. (2019) [30] First-line treatment with chemotherapy and/or hormone therapy First-line treatment with chemotherapy and/or hormone therapy 60% received first-line treatment with hormone therapy, 39% received chemotherapy, and 42% of patients received anti-HER2 therapy
Vyas et al. (2021) [5] Receipt of initial systemic therapy within 6 months of secondary (metastatic) breast cancer diagnosis Unspecified systemic anticancer therapy 72.3% received initial (guideline concordant) systemic therapy within 6 months of secondary (metastatic) breast cancer diagnosis
Wan & Jubelirer (2015) [35] Receipt of chemotherapy within 6 months of diagnosis Chemotherapy 30.2% received chemotherapy
Wang & Du (2015) [42] Receipt of hormone therapy 1 year post initiation (stratified by chemotherapy use) Hormone (endocrine) therapy 70.8% received hormone therapy
Wolfson et al. (2015) [43]

Receipt of care which included un specified SACT

SACT at a National Cancer Institute Comprehensive Cancer Centre (NCI CCC)

Nonspecified SACT

**22–39 years

9.7%

40–65 years 90.3%