Table 2.
Mendelian randomization estimates of the associations from dietary habits on common risk factors of colorectal cancer
| Outcome | Causal effect (95% CI); p value | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Alcohol | Coffee | Fruit | Meat | Milk | Sweets | Tea | Vegetables | Yogurt-ice | |
| DM | 1.32 (0.80-2.20); 0.278 | 1.05 (0.86-1.28); 0.649 | 2.44 (0.53-11.34); 0.255 | 0.95 (0.59-1.51); 0.819 | 1.19 (0.52-2.72); 0.673 | 0.79 (0.50-1.26); 0.330 | 1.14 (0.83-1.57); 0.406 | 0.91 (0.11-7.62); 0.931 | 0.98 (0.41-2.38); 0.972 |
| Family history | 1.00 (0.99-1.00); 0.608 | 1.00 (0.99-1.01); 0.897 | 1.02 (0.99-1.06); 0.060 | 1.00 (0.99-1.01); 0.483 | 1.00 (0.99-1.01); 0.806 | 1.01 (0.99-1.01); 0.196 | 1.00 (0.99-1.01); 0.823 | 0.99 (0.98-1.01); 0.902 | 0.99 (0.98-1.00); 0.140 |
| IBD | 1.22 (0.82-1.82); 0.331 | 1.06 (0.90-1.24); 0.491 | 0.69 (0.16-3.03); 0.626 | 1.33 (0.90-1.97); 0.150 | 0.77 (0.36-1.63); 0.487 | 1.12 (0.79-1.60); 0.524 | 1.02 (0.60-1.74); 0.929 | 1.13 (0.40-3.23); 0.816 | 1.09 (0.54-2.18); 0.820 |
| Tobacco | 0.99 (0.20-4.99); 0.993 | 1.67 (0.80-3.48); 0.170 | 0.01 (0.02-3.36); 0.110 | 0.50 (0.09-2.68); 0.414 | 0.93 (0.03-33.61); 0.969 | 0.98 (0.13-7.14); 0.982 | 2.67 (0.63-11.28); 0.182 | 0.17 (0.01-9.68); 0.397 | 0.18 (0.01-136.28); 0.286 |
Abbreviation: DM, Diabetes; IBD, Inflammatory Bowel Disease