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. 2024 Jan 17;25:23. doi: 10.1186/s12882-024-03463-8

Table 2.

Cox regression model eGFR hazard ratios for all-cause and CVD mortality among patients with type 2 diabetes stratified by age using 65 years as cut-off and gender, with eGFR between 90 and 119 mL/min per 1.73 m2 as reference (N = 36,556; years 2013–2019)

eGFR categories (mL/min per 1.73 m2) < 65 years ≥65 years
Number of Deaths (incidence rate (%) Malea) Hazard Ratio (95% CI) Male Number of Deaths (incidence rate (%) Femalea) Hazard Ratio (95% CI) Female Number of Deaths (incidence rate (%) Malea) Hazard Ratio (95% CI) Male Number of Deaths (incidence rate (%) Femalea) Hazard Ratio (95% CI) Female
All-cause mortality
 < 30 2 (31.25) 6.63 (1.64, 26.70) 5 (64.94) 22.88 (9.36, 55.94) 32 (66.12) 4.19 (2.86, 6.13) 42 (51.92) 6.90 (4.89, 9.74)
 30 - < 60 17 (7.13) 1.44 (0.88, 2.38) 18 (9.23) 3.01 (1.84, 4.94) 333 (33.89) 2.05 (1.69, 2.47) 270 (23.65) 3.03 (2.47, 3.71)
 60 - < 90 103 (5.54) 1.12 (0.88, 1.43) 53 (5.17) 1.68 (1.22, 2.32) 536 (20.19) 1.20 (1.00, 1.44) 489 (16.30) 2.06 (1.71, 2.49)
 90 - < 120 172 (4.95) 1.00 (Reference) 127 (3.08) 1.00 (Reference) 152 (16.90) 1.00 (Reference) 141 (7.99) 1.00 (Reference)
CVD mortality
 < 30 1 (15.63) 9.58 (1.33, 69.14) 3 (38.96) 59.64 (18.16, 195.91) 9 (18.60) 4.72 (2.28, 9.79) 17 (21.01) 14.43 (7.87, 26.48)
 30 - < 60 8 (3.35) 1.98 (0.95, 4.15) 7 (3.59) 5.13 (2.25, 11.71) 95 (9.67) 2.38 (1.63, 3.48) 88 (7.71) 5.13 (3.33, 7.89)
 60 - < 90 37 (1.99) 1.17 (0.78, 1.77) 12 (1.17) 1.67 (0.85, 3.27) 143 (5.39) 1.31 (0.91, 1.88) 118 (3.93) 2.59 (1.71, 3.94)
 90 - < 120 59 (1.70) 1.00 (Reference) 29 (0.70) 1.00 (Reference) 37 (4.11) 1.00 (Reference) 27 (1.53) 1.00 (Reference)

Unadjusted model: Abbreviations: eGFR estimated glomerular filtration rate, CVD cardiovascular disease

aThe incidence rate represented is for per 1000 person-years