Table 3.
Cox regression simplified model (excluding living in rental block) eGFR hazard ratios for all-cause and CVD mortality among patients with type 2 diabetes stratified by age using 65 years as cut-off and gender, with eGFR between 90 and 119 mL/min per 1.73 m2 as reference (N = 36,556; years 2013–2019)
| eGFR categories (mL/min per 1.73 m2) | < 65 years | ≥65 years | ||
|---|---|---|---|---|
| Male | Female | Male | Female | |
| All-cause mortality | ||||
| < 30 | 4.97 (1.23, 20.04) | 18.22 (7.49, 44.32) | 3.26 (2.22, 4.78) | 5.73 (4.05, 8.10) |
| 30 - < 60 | 1.29 (0.79, 2.13) | 2.75 (1.68, 4.51) | 1.88 (1.55, 2.28) | 2.63 (2.14, 3.22) |
| 60 - < 90 | 1.12 (0.88, 1.43) | 1.64 (1.19, 2.25) | 1.17 (0.98, 1.40) | 1.92 (1.59, 2.32) |
| 90 - < 120 | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| CVD mortality | ||||
| < 30 | 6.11 (0.84, 44.20) | 40.63 (13.09, 126.15) | 2.80 (1.35, 5.84) | 10.02 (5.44, 18.46) |
| 30 - < 60 | 1.51 (0.72, 3.16) | 4.03 (1.76, 9.22) | 1.87 (1.27, 2.74) | 3.87 (2.51, 5.97) |
| 60 - < 90 | 1.09 (0.73, 1.65) | 1.50 (0.77, 2.95) | 1.19 (0.83, 1.72) | 2.22 (1.46, 3.37) |
| 90 - < 120 | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
Model: Elapsed time to all-cause/CVD mortality = eGFR + age + gender + eGFR*age + eGFR*gender + age*gender + eGFR*age*gender + covariates. Covariates: ethnicity, smoking, body mass index, lipid medications, established CVD, albuminuria. Abbreviations: eGFR estimated glomerular filtration rate, CVD cardiovascular disease