| Subcutaneous route |
Medical application = certainty of administration |
Regular visits to the doctor (time-consuming) |
| Frequent doctor/patient contact > regular monitoring of the course of the AIT, side effects and underlying illness(es) of the patients |
Possible anxiety-inducing injections |
|
At least 30 minutes monitoring time after the injection |
| Risk of systemic allergic reactions (very rare) |
| Risk of local side effects (frequent) |
| Sublingual Route |
Not painful |
Risk of local side effects (very common, usually mild and self-limiting) |
| Can be administered at home (usually first application at the doctor’s office with 30-minute monitoring) |
Usually daily application necessary over a longer period (pre/co-seasonal i.e. several months or perennial > daily “reminder”) |
| Small number of visits to the doctor/physician required |
Mucosal contact over 2 minutes and patient motivation required (check especially with children) |
| Very low risk of systemic reactions (lower than with SCIT) |
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