PdI for TC-CS-SP NPs prepared at optimal CS to SP molar ratios (1 : 1) incubated at different phosphate buffer (pH 6, pH 7.4) at different temperature (mean ± SD, n = 3).

PdI
Temperature	37 °C		4 °C
Time (h)	pH 7.4	pH 6	pH 7.4	pH 6
24	0.3	0.3	0.3	0.2
48	0.3	0.3	0.3	0.2
168	0.4	0.3	0.3	0.2