IC₅₀ values of MTT assay after incubating the treatments with the cells.

IC50 (μM)
Treatment	TC	TC-CS-SP NPsa at 37 °C	TC-CS-SP NPs at 40 °C	CS-SP NPsa at 37 °C	CS-SP NPsa at 40 °C
MCF7	18.31 ± 2.44	3.89 ± 0.33	1.12 ± 0.42	10.97 ± 3.37	8.94 ± 3.63
MDA-MB-231	17.24 ± 2.86	3.84 ± 0.47	4.84 ± 0.67	13.14 ± 1.29	8.04 ± 3.80
HDF	24.89 ± 2.26	15.07 ± 1.20	16.84 ± 2.59	26.29 ± 1.67	>100

^aNPs were prepared at optimal CS to SP molar ratios (1 : 1).