Figure 11.

AZD8797 suppress the CX3CL1/CX3CR1 signaling pathway. (A and B) The number of CX3CL1 and CX3CR1 positive cells in the RD + AZD8797 group, reduced significantly compared with the RD group. (C, D, and E) Western blot results showed that the protein levels of CX3CL1, CX3CR1, and p-NF-κB in the RD + AZD8797 group reduced significantly compared with the RD group, the expression levels of CX3CL, CX3CR1, and NF-κB protein were analyzed by Western blot assay. NF-κB and statistical line chart of gray value. (Scale = 20 µm; *P < 0.05, **P < 0.01, and ****P < 0.0001, for differences compared with the normal control, and ^#P < 0.05, ^##P < 0.01, and ^###P < 0.001, for differences between animal groups, n = 6).