Table 3. Summary of findings: Healthcare facility use of an airborne precaution room versus an adequately ventilated room for mpox patients for reducing mpox infection.

Population: Adults and children with mpox Intervention: Airborne precaution room Comparator: Adequately ventilated room Setting: Inpatient and outpatient
Outcome	Study results and measurements	Absolute effect estimates transmission		Certainty of evidence	Comment
		Adequately ventilated single room	Airborne precaution room
Mpox infection inferred from transmission route frequency dataa	No reported cases of transmission by inhalation in 4309 patients (114 studies) Inferred odds ratiob: 1	Uncertainc	Uncertain, but no different to adequately ventilated roomd	⨁⨁⨁⊝ Moderatee Due to indirectness	The use of an airborne precaution room probably has no impact on preventing mpox transmission compared to an adequately ventilated room

^aNo studies identified that directly informed the research question; data from route of transmission frequency resulting in mpox infection was inferred.

^bReview findings indicated that mpox was transmitted in almost all occasions by direct physical contact; no cases of transmission through inhalation were identified. The review team inferred that if there are no or almost no cases of transmission by inhalation there would be no difference between the intervention and comparator groups.

^cWe could not estimate the baseline transmission risk due to absence of data.

^dWe could not estimate the risk in the intervention group due to an unknown baseline risk in the comparator group.

^eRated down one level for indirectness due to limited data on route of transmission frequency for Clade I mpox virus.