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. 2024 Feb 1;15(1):43–73. doi: 10.14336/AD.2023.0608

Table 2.

List of common drugs used for AD.

Drug Pros Effectiveness Action mechanism Reference
Donepezil Improving cognition and function, delaying institutionalization Moderate Acetylcholinesterase inhibitor [249]
Rivastigmine Improving cognition and function, delaying institutionalization Moderate Acetylcholinesterase inhibitor [250]
Galantamine Improving cognition and function, delaying institutionalization Moderate Acetylcholinesterase inhibitor and allosteric modulator of nicotinic receptors [251]
Memantine Improving cognition and function, delaying institutionalization Moderate NMDA receptor antagonist [252]
Solanezumab Slowing down degeneration process through increasing Aβ clearance Limited Remove soluble Aβ [253]
Memantine and donepezil Memantine plus donepezil showing superior outcomes Limited Combination of acetylcholinesterase inhibitor and NMDA receptor antagonist [254]
Huperzine A Improving cognition and function Limited Acetylcholinesterase inhibitor [255]
Ginkgo biloba Improving cognition and function Limited Antioxidant, anti-inflammatory, and circulatory effects [256]
NSAIDs No significant effect on cognition or overall AD severity. Limited Anti-inflammatory effect [257]
Statins May reduce risk of Alzheimer's disease Limited Cholesterol-lowering effect [258]
Antidepressants Improving mood and reducing behavioral symptoms Limited Various mechanisms [259]