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Structural schematics of select NLRs. Diagrams of the domain organization of all NLRs discussed in this review, organized into NLR families based on N-terminal domains.
Abbreviations: AD, acidic activation domain; CARD, caspase activating and recruitment domain; FIIND, function to find domain; LRR, leucine-rich repeat; PYD, pyrin domain; NACHT, domain present in NAIP, CIITA, HET-E, and TP-1; NAD, NACHT-associated domain. Created with BioRender.com.
