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. 2024 Jan 18;14:1655. doi: 10.1038/s41598-024-51918-7

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© The Author(s) 2024, corrected publication 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Genetic and expression variation of mitotic catastrophe-related genes (MCRGs) in colon adenocarcinoma (COAD). (A) Volcano plot of differentially expressed MCRGs. (B) Forest plot of univariate Cox analysis showing the 23 MCRGs significantly associated with OS in colon cancer patients. (C) Expression of 23 MCRGs in COAD and normal colon tissues. The upper and lower ends of the boxes indicate the interquartile range of values. Lines in the boxes represent medians. *P < 0.05, ***P < 0.001. (D) Copy number variation (CNV) frequencies of the 23 MCRGs in the COAD cohort. (E) Location of CNV alterations in 23 MCRGs on 23 chromosomes in the cohort. (F) Mutation frequencies and classification of 23 MCRGs in COAD.