Table 3.

Comparison of salivary metabolite concentrations between OLP patients (N = 15) and healthy controls. (N = 15). The metabolites that lacked at least one value were not included in the statistical assessment

Metabolite	OLP patients mean ± SD	Controls mean ± SD	p value	Pooled saliva mean
SCFAs
Acetate	1971.7 ± 781.1	1503.0 ± 715.2	0.048*	1687.0
Butyrate	23.2 ± 20.9	16.4 ± 10.9	0.314	15.5
Formate	152.0 ± 195.0	80.1 ± 63.3	0.192	168.0
Propionate	284.3 ± 205.7	235.7 ± 156.2	0.472	248.0
Amino acids
Alanine	13.8 ± 13.2	11.4 ± 7.3	0.267	14.3
Glycine	50.9 ± 25.5	51.5 ± 35.4	0.871	82.8
Phenylalanine	9.3 ± 5.4	8.5 ± 3.6	0.818	11.5
Taurine	110.5 ± 49.6	48.3 ± 29.0	0.271	38.7
Proline	133.5 ± 114.5	59.1 ± 44.1	0.212	116.1
Histidine	23.3 ± 11.8	-	-	-
Tyrosine	24.6 ± 12.5	89.6 ± 11.4	0.003**	103.3
Organic acids
Citrate	19.1 ± 7.9	18.3 ± 13.8	0.996	22.2
Lactate	265.6 ± 140.4	198.3 ± 174.5	0.255	155.3
Pyruvate	17.6 ± 11.2	10.4 ± 7.8	0.032*	12.8
Succinate	33.8 ± 32.1	28.2 ± 15.7	0.549	18.9
Amines
Methylamine	12.1 ± 1.3	2.0 ± 0.9	0.006**	1.5
Trimethylamine	1.4 ± 1.4	-	-	-
Other
Choline	9.4 ± 5.3	4.1 ± 2.0	0.292	4.2
Isopropanol	2.47 ± 0.9	-	-	-
1.2-propanediol	-	27.3 ± 14.2	-	19.1
Butanol	17.1 ± 8.1	8.6 ± 5.8	0.126	15.5
Methanol	28.5 ± 17.5	27.7 ± 9.2	0.878	22.6
Fucose	46.5 ± 30.9	66.3 ± 40.3	0.167	62.8

SCFAs short chain fatty acids

**p < 0.05