Table 1.
Baseline demographic and patient characteristics
| Characteristic | Clinical benefit | |
|---|---|---|
| Yes (n = 4) | No (n = 6) | |
| Median age (years) | 60.5 (range) | 58.0 (range) |
| Median weight (kg) | 93.1 (range) | 70.7 (range) |
| Median BMI | 28.3 (range) | 28.1 (range) |
| All | CB | NCB | ||||
|---|---|---|---|---|---|---|
| n | % | n | % | n | % | |
| Female | 7 | 70.0 | 1 | 25.0 | 6 | 100.0 |
| Male | 3 | 30.0 | 3 | 75.0 | – | – |
| Race | ||||||
| Unknown | 2 | 20.0 | – | – | 2 | 33.3 |
| White | 8 | 80.0 | 4 | 100.0 | 4 | 66.7 |
| Ethnicity | ||||||
| Not Hispanic/Latino | 9 | 90.0 | 3 | 75.0 | 6 | 100.0 |
| Unknown | 1 | 10.0 | 1 | 25.0 | – | – |
| ECOG performance status | ||||||
| 0 | 5 | 50.0 | 1 | 25.0 | 4 | 66.7 |
| 1 | 5 | 50.0 | 3 | 75.0 | 2 | 33.3 |
| Primary site of disease | ||||||
| Anus | 2 | 20.0 | 1 | 25.0 | 1 | 16.7 |
| Eye, globe | 1 | 10.0 | 1 | 25.0 | – | – |
| Melanoma (eye) | 1 | 10.0 | 1 | 25.0 | – | – |
| Nasopharynx | 1 | 10.0 | 1 | 25.0 | – | – |
| Shoulder | 1 | 10.0 | – | – | 1 | 16.7 |
| Sinuses | 1 | 10.0 | – | – | 1 | 16.7 |
| Skin | 1 | 10.0 | – | – | 1 | 16.7 |
| Temple | 1 | 10.0 | – | – | 1 | 16.7 |
| Thigh | 1 | 10.0 | – | – | 1 | 16.7 |
| Disease stage | ||||||
| Stage III | 1 | 10.0 | 1 | 25.0 | – | – |
| Stage IIIB | 1 | 10.0 | – | – | 1 | 16.7 |
| Stage IV | 8 | 80.0 | 3 | 75.0 | 5 | 83.3 |
| Prior therapy | ||||||
| Chemotherapy | 3 | 30.0 | 2 | 50.0 | 1 | 16.67 |
| Immunotherapy | 10 | 100.0 | 4 | 100.0 | 6 | 100.0 |
| Radiation | 4 | 40.0 | 1 | 25.0 | 3 | 50.0 |
| Surgery | 10 | 100.0 | 4 | 100.0 | 6 | 100.0 |
BMI body mass index, ECOG Eastern Cooperative Oncology Group, NCB no clinical benefit, and CB clinical benefit