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Relationship between exerkines and myokines. Exerkines are factors that are induced by exercise in various organs. Myokines are factors secreted by muscles and not necessarily induced by exercise. As depicted in the figure, a noticeable overlap exists between exerkines and myokines. The overlapping segment represents factors induced in muscles as a result of exercise, which may serve as the molecular foundation for elucidating the health-promoting effects of physical activity.
