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. 2024 Jan 5;10:1298424. doi: 10.3389/fmed.2023.1298424

Table 1.

Top 10 compounds identified from tertiary screen in Figure 1.

PPI Top compounds MW Concentration (μM) Agonist Concentration (μg/mL)
1 Cucurbitacin I 514.65 10 LPS 0.1
2 Costunolide 232.32 10 Pam2 0.1
3 MLN120B 366.80 10 Pam2 0.1
4 (−)-Parthenolide 248.32 10 Pam2 0.1
5 Peficitinib 326.39 1 Pam2 0.1
6 Oclacitinib maleate 453.51 1 R848 12.5
7 AD80 473.43 1 Pam2 0.1
8 Cucurbitacin B 558.70 1 R848 12.5
9 CEP-33779 462.57 1 R848 12.5
10 Dehydrocostus lactone 230.30 1 Pam2 0.1