Table 2.
Inhibition of 17 clinical isolates of canine periodontal disease and 2 standard strains of bacteria by 6 drugs in vitro.
| Clinical strains of PD canines | EGCG (mg/mL) | CD (mg/mL) | MDZ (μg/mL) | CC (μg/mL) | MER (μg/mL) | AC (μg/mL) |
|---|---|---|---|---|---|---|
| BX6 Propionibacterium acnes | 1.25 | 12.5 | R | R | 0.8 | 1.28 |
| 6 L33 Macrococcus spp. | 1.25 | 6.25 | R | 12.8 | 0.8 | 0.64 |
| 6R82 Actinomyces bowdenii | 0.5 | 3.125 | R | 3.2 | 0.8 | 0.16 |
| 6 L31 Peptostreptococcus micros | 1.25 | 6.25 | R | 3.2 | 0.8 | 0.16 |
| 6R81 Actinomyces weissii | 1.25 | 50 | R | 3.2 | 0.8 | R |
| BX5 Prevotella intermedia | 1 | 12.5 | 1.6 | 3.2 | 0.8 | 2.56 |
| SY10B Porphyromonas crevioricanis | 1.25 | R | R | 3.2 | 0.8 | R |
| 6 L32 Uncultured bacterium clone | 1.25 | R | R | R | 0.8 | 0.16 |
| W83 Porphyromonas gingivalis | 0.078 | 1.56 | 1.6 | 6.4 | 0.8 | 0.16 |
| Y1 Fusobacterium spp. canine oral taxon | 1.25 | 1.56 | R | 25.6 | 1.6 | R |
| SY10B Porphyromonas crevioricanis | 1.25 | 1.56 | 1.6 | R | 0.8 | R |
| 6MN Propionibacterium acnes | 1.25 | 12.5 | 1.6 | R | 6.4 | R |
| SB45 Prevotella intermedia | 1.25 | 3.125 | R | 25.6 | 1.6 | 0.16 |
| SB46 Prevotella intermedia | 1.25 | 3.125 | R | 1.6 | 0.8 | 0.64 |
| ATCC 51700 Porphyromona gulae | 0.019 | 1.56 | 1.6 | 1.6 | 0.8 | 0.16 |
| SB40 Porphyromonas gulae | 0.625 | 6.25 | 1.6 | 1.6 | 0.8 | 0.16 |
| SB41 Prevotella intermedia | 0.0625 | 12.5 | 1.6 | 1.6 | 0.8 | 0.16 |
| SB42 Porphyromonas gulae | 0.019 | 3.125 | 1.6 | 1.6 | 0.8 | 0.16 |
| SB43 Prevotella intermedia | 1.25 | 12.5 | 1.6 | 1.6 | 0.8 | 0.16 |
Chlorhexidine, CD; Metronidazole, MDZ; Clindamycin, CC; Meropenem, MER; Amoxicillin and Clavulanate Potassium, AC.