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. 2024 Jan 5;14:1329772. doi: 10.3389/fmicb.2023.1329772

Table 2.

Inhibition of 17 clinical isolates of canine periodontal disease and 2 standard strains of bacteria by 6 drugs in vitro.

Clinical strains of PD canines EGCG (mg/mL) CD (mg/mL) MDZ (μg/mL) CC (μg/mL) MER (μg/mL) AC (μg/mL)
BX6 Propionibacterium acnes 1.25 12.5 R R 0.8 1.28
6 L33 Macrococcus spp. 1.25 6.25 R 12.8 0.8 0.64
6R82 Actinomyces bowdenii 0.5 3.125 R 3.2 0.8 0.16
6 L31 Peptostreptococcus micros 1.25 6.25 R 3.2 0.8 0.16
6R81 Actinomyces weissii 1.25 50 R 3.2 0.8 R
BX5 Prevotella intermedia 1 12.5 1.6 3.2 0.8 2.56
SY10B Porphyromonas crevioricanis 1.25 R R 3.2 0.8 R
6 L32 Uncultured bacterium clone 1.25 R R R 0.8 0.16
W83 Porphyromonas gingivalis 0.078 1.56 1.6 6.4 0.8 0.16
Y1 Fusobacterium spp. canine oral taxon 1.25 1.56 R 25.6 1.6 R
SY10B Porphyromonas crevioricanis 1.25 1.56 1.6 R 0.8 R
6MN Propionibacterium acnes 1.25 12.5 1.6 R 6.4 R
SB45 Prevotella intermedia 1.25 3.125 R 25.6 1.6 0.16
SB46 Prevotella intermedia 1.25 3.125 R 1.6 0.8 0.64
ATCC 51700 Porphyromona gulae 0.019 1.56 1.6 1.6 0.8 0.16
SB40 Porphyromonas gulae 0.625 6.25 1.6 1.6 0.8 0.16
SB41 Prevotella intermedia 0.0625 12.5 1.6 1.6 0.8 0.16
SB42 Porphyromonas gulae 0.019 3.125 1.6 1.6 0.8 0.16
SB43 Prevotella intermedia 1.25 12.5 1.6 1.6 0.8 0.16

Chlorhexidine, CD; Metronidazole, MDZ; Clindamycin, CC; Meropenem, MER; Amoxicillin and Clavulanate Potassium, AC.