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Clinical prognosis analysis. (A) DDR-activated subtypes exhibited poorer OS. (B) DDR-activated subtypes exhibited poorer DFS. (C-F) The DDR-activated subgroup had a higher incidence of advanced M stage, advanced pathologic stage, and higher grade N stage. (G,H) Females and older individuals were more frequently observed in the DDR-suppressed subgroups. **, 0.01≤P<0.05; ***, P<0.01. OS, overall survival; HR, hazard ratio; DFS, disease-free survival; DDR, DNA damage repair.
