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Analysis of differentially expressed DDR-related genes in LUAD. (A) Volcano plot depicting differential gene expression between cluster 1 and cluster 2, revealing 604 upregulated genes and 933 downregulated genes. (B) Abundance of highly expressed genes observed in the DDR-activated subgroups (cluster 2). (C) Upregulation of UBD, EID3, SMC1B, DMC1, and CDKN2A in the DDR-activated subgroups in contrast to the DDR-suppressed subgroups. DDR, DNA damage repair; LUAD, lung adenocarcinoma.
