Table 1. Preoperative characteristics of two groups: LTR or surgical resection of lung cancer.
| Characteristics of patients | All | Transplant | Cancer surgery | P |
|---|---|---|---|---|
| N | 365 | 160 (43.8) | 205 (56.2) | – |
| Sex | <0.001 | |||
| Male | 277 (75.9) | 99 (61.9) | 178 (86.8) | |
| Female | 88 (24.1) | 61 (38.1) | 27 (13.2) | |
| Age (years) | 64.11±8.43 | 58.85±5.59 | 68.20±7.99 | <0.001 |
| Height (cm) | 167.25±8.69 | 164.65±8.98 | 169.25±7.92 | <0.001 |
| Weight (kg) | 70.25±13.59 | 66.70±11.55 | 78.39±14.48 | <0.001 |
| BMI (kg/m2) | 25.06 [22.34–28] | 24.04 [22.14–27.07] | 27.36 [24.82–30.48] | <0.001 |
| HTN | 143 (39.2) | 30 (18.8) | 113 (55.1) | <0.001 |
| Dyslipidemia | 150 (41.1) | 43 (26.9) | 107 (52.2) | <0.001 |
| Diabetes | 50 (13.7) | 10 (6.3) | 40 (19.5) | <0.001 |
| Smoking | <0.001 | |||
| Never-smoker | 4 (1.1) | 3 (1.9) | 1 (0.5) | |
| Former smoker | 302 (82.7) | 157 (98.1) | 145 (70.7) | |
| Active smoker | 59 (16.2) | 0 (0) | 59 (28.8) | |
| Tobacco consumption (packs-year) | 46.50 [35–60] | 40 [30–60] | 50 [40–70] | <0.001 |
| α1-antitrypsin (mg/dL) | 139 [109–154] | 134.5 [102–155.5] | 147 [142–153] | 0.236 |
| Need for O2† | <0.001 | |||
| Nocturnal | 4 (1.1) | 2 (1.3) | 2 (1.0) | |
| At rest | 140 (39.1) | 140 (90.3) | 0 | |
| Exertion | 6 (1.7) | 6 (3.9) | 0 | |
| Not needed | 208 (58.1) | 7 (4.5) | 201 (99.0) | |
| FVC (mL) | 2,939.97±983.71 | 2,292.12±803.77 | 3,463.48±784.76 | <0.001 |
| FVC (%) | 82.21±23.55 | 65.81±17.87 | 95.19±18.96 | <0.001 |
| FEV1 (mL) | 1,410 [670–2,000] | 630 [510–797.5] | 1,930 [1,630–2,360] | <0.001 |
| FEV1 (%) | 43 [24–73] | 23 [19.82–27.6] | 71 [60–82] | <0.001 |
| FEV1/FVC | 48 [31–61.64] | 30 [26–35.5] | 59.54 [51.86–65.87] | <0.001 |
| DLCO (%) | 43.4 [26.4–70] | 32 [22.25–44.5] | 75.2 [52.75–92.25] | <0.001 |
| PaO2 (mmHg) | 59.51±9.18 | 56.99±8.11 | 67.91±7.46 | <0.001 |
| PaCO2 (mmHg) | 44.78±81.6 | 45.74±7.94 | 38.93±7.05 | <0.001 |
| Creatinine (mg/dL) | 0.79 [0.65–0.93] | 0.68 [0.57–0.80] | 0.86 [0.74–1.02] | <0.001 |
| Cholesterol (mg/dL) | 189.73±42.98 | 195.18±42.21 | 176.84±42.33 | 0.003 |
| Albumin (g/dL) | 4.3 [4.1–4.5] | 4.4 [4.2–4.6] | 4.3 [4.1–4.4] | <0.001 |
| CRP (mg/dL) | 0.8 [0.4–1.7] | 0.4 [0.4–1.27] | 1.2 [0.5–3.5] | 0.019 |
| ESR (mm) | 17 [8–31] | 16 [7–29] | 24 [11.5–43] | 0.101 |
| Fibrinogen (mg/dL) | 417 [335–530] | 417 [340–530] | 417 [320.5–533.25] | 0.72 |
| Platelets (×103/µL) | 230.000 [188.500–269.500] |
230.000 [189.000–266.500] |
229.000 [187.000–279.500] |
0.832 |
†, there are five and two missing values (lack of information) in the “Transplant” and “Cancer surgery” groups, respectively. Continuous quantitative variables are expressed as mean ± standard deviation for normally distributed variables and as median [interquartile range] for non-normally distributed data. Categorical variables were expressed as frequencies (percentages). LTR, lung transplant recipients; N, number; cm, centimeter; kg, kilogram; mg, milligram; BMI, body mass index; HTN, arterial hypertension; FVC, forced vital capacity; FEV1, forced expiratory volume in the first second; DLCO, diffusing capacity for carbon monoxide; Pa, arterial pressure; O2, oxygen; CO2, carbon dioxide; mmHg, millimeters of mercury; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; µL, microliter; dL, deciliter; mL, milliliter.