Table 1. Clinical data between two groups of patients.
| Variables | Standard group (n=74) | HFNC group (n=77) | t/χ2/U | P |
|---|---|---|---|---|
| Age (years) | 67.78±16.82 | 66.97±17.08 | 0.293 | 0.77 |
| Male | 55 (74.3) | 46 (59.7) | 3.624 | 0.075 |
| BMI (kg/m2) | 23.10±4.15 | 23.46±4.13 | −0.527 | 0.599 |
| APACHE-II | 17.51±5.47 | 17.78±5.44 | −0.299 | 0.756 |
| Causes of respiratory failure | 4.272 | 0.37 | ||
| CAP | 35 (47.3) | 29 (37.7) | 1.85 | 0.4 |
| HAP | 9 (12.2) | 11 (14.3) | 0.366 | 0.61 |
| AECOPD | 15 (20.3) | 11 (14.3) | 1.254 | 0.64 |
| Extrapulmonary sepsis | 7 (9.5) | 12 (15.6) | 1.256 | 0.65 |
| Other | 8 (10.8) | 14 (18.2) | 0.958 | 0.58 |
| Bilateral lung disease | 71 (95.9) | 73 (94.8) | 0.111 | 0.739 |
| Respiratory rate (times/min) | 26.22±7.28 | 24.83±5.98 | 1.277 | 0.204 |
| Heart rate (beats/min) | 103.81±20.43 | 107.39±25.22 | −0.955 | 0.341 |
| Blood pressure (mmHg) | ||||
| SAP | 134.52±24.70 | 132.07±27.91 | 0.566 | 0.572 |
| MAP | 96.07±17.82 | 91.36±17.52 | 1.632 | 0.105 |
| Arterial blood gases | ||||
| pH | 7.37±0.12 | 7.40±0.10 | −1.529 | 0.128 |
| PaCO2 (mmHg) | 47.57±25.4 | 42.40±18.06 | −0.866 | 0.387 |
| PaO2 (mmHg) | 102.55±53.07 | 97.96±49.25 | 0.552 | 0.582 |
| Oxygenation index | 226.50±103.93 | 225.20±99.67 | 0.078 | 0.938 |
Data are presented as n (%) or mean ± standard deviation. BMI, body mass index; APACHE-II, Acute Physiology and Chronic Health Evaluation-II; CAP, community-acquired pneumonia; HAP, hospital acquired pneumonia; AECOPD, acute exacerbation of chronic obstructive pulmonary disease; SAP, stroke-associated pneumonia; MAP, mean arterial pressure; PaCO2, carbon dioxide partial pressure; PaO2, partial pressure of arterial oxygen.