Figure 2.

Design rationale of conduction‐dominated cryomesh. A) Heat transfer model of a cryomesh cooling in LN₂. The right boundary is insulated to consider the conduction‐dominated limiting case. B) Thermal resistances of convection interface, mesh, and biosystem. A Biot number (Bi) value (Equation (5)) <0.01 indicates that the cryomesh is operating in a conduction‐dominated mode. Area shown in yellow indicates “conduction‐dominated” behavior. L _c is the critical length related to wire diameter and pore size (Table S2, Supporting Information). The thermal properties are included in Table S3, Supporting Information. C) Reduced mesh wire diameter, D, increases the contact area and decreases the heat release time. The heat release time t has an inverse correlation with the cooling rate (CR), that is, t ≈ ΔT/CR. D) Heat release time increases with increase of biosystem thickness. A conductive cryomesh reduces the heat release time for a thick biosystem.